The number of first responders who have died from 9/11-related illnesses now almost equals the number of firefighters who died during the terror attacks themselves.

Sepsis is an illness that affects nearly 50 million people worldwide each year, with around 11 million deaths attributed to the condition. In the United States, at least 1.7 million adults in the US develop sepsis annually, and nearly 270,000 die as a result, the Centres for Disease Control and Prevention (CDC) says. It affects 245,000 people in the UK each year, with around 48,000 deaths, according to the UK Sepsis Trust. World Sepsis Day commemorated on 13th September every year, strives to raise global awareness of the life-threatening condition. The day is seen as “an opportunity for people worldwide to unite in the fight against sepsis,” the Global Sepsis Alliance says. Here is everything you need to know about sepsis: What is sepsis? Sepsis Research says when the condition strikes, the immune system “overreacts” and begins to attack the infection and everything else around it “including the body’s own tissues and organs.” “Any type of infection — bacterial, viral or fungal — can lead to sepsis,” it adds. When sepsis occurs, it can cause inflammation and cause blood clotting around the body, if it does not get treated, it can result in death, organ failure and tissue damage, CDC says. Sepsis cannot be caught from another person, the NHS explains. What are the symptoms? The World Health Organisation (WHO) explains that the condition is a “medical emergency,” so if you think a person is exhibiting signs of sepsis or if you are showing signs – make sure you call 999 or go to the emergency room immediately. According to WHO, common signs and symptoms include: • Fever or low temperature and shivering • Confusion • Difficulty breathing • Clammy or sweaty skin • Extreme body pain or discomfort • High heart rate, weak pulse or low blood pressure • Low urine output Symptoms in children include: • Fast breathing • Convulsions • Pale skin • Lethargy • Difficulty waking up • Feeling cold to touch What are the causes? The Mayo Clinic says any type of infection can lead to sepsis and those that more commonly cause the condition include infections of: • Lungs, such as pneumonia • Kidney, bladder and other parts of the urinary system • Digestive system • Bloodstream • Catheter sites • Wounds or burns “Sepsis often presents as the clinical deterioration of common and preventable infections such as those of the respiratory, gastrointestinal and urinary tract, or of wounds and skin. Sepsis is frequently under-diagnosed at an early stage - when it still is potentially reversible,” the Global Sepsis Alliance says. Who is most at risk? The people most at risk of the condition, according to Mayo Clinic, are: • People with lower immune response, such as those being treated for cancer • People with human immunodeficiency virus (HIV). • People with chronic diseases such as diabetes kidney disease or chronic obstructive pulmonary disease (COPD). • people who are in intensive care or longer hospital stays. • People over the age of 65 • Infants How many cases are there globally? The WHO says a scientific publication estimated that in 2017 there were 48.9 million cases and 11 million sepsis-related deaths worldwide, which accounted for almost 20 per cent of all global deaths. That same year, almost half of all global sepsis cases occurred among children with an estimated 20 million cases and 2.9 million global deaths in children under 5 years of age. How can it be prevented? The Global Sepsis Alliance says the best to to avoid sepsis is by preventing infection. This can be done by undergoing vaccinations, ensuring that you only come into contact with clean water, washing your hands properly and if you are giving birth - making sure it is in a clean and sterilised environment. Can sepsis be treated? Sepsis can be treated with appropriate treatment such as antibiotics – this should be given as soon as possible. The CDC says sometimes “surgery is required to remove tissue damaged by the infection”. “Antibiotics are critical tools for treating life-threatening infections, like those that can lead to sepsis,” the CDC adds. Read More 5 things everyone needs to know about eczema 13 potential cancer symptoms you should get checked out How can I improve my teenager’s low mood? Duran Duran’s Andy Taylor says he’s ‘asymptomatic’ after end-of-life diagnosis Nine hours of parallel surgery: how Britain’s first womb transplant was carried out Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’

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Heidi Klum is prepping for the debut of her own creation – her 2023 Halloween costume. From a flesh-eating alien to Fiona and a sparkly firework, the 50-year-old supermodel not only stunts on high-fashion runways but on the red carpet for the spookiest night of the year. It’s safe to say Klum’s love for dressing up isn’t just haute couture. She’s a costume enthusiast as well, and the mother of three is already preparing to assume her character for this year’s Halloween celebration. The America’s Got Talent judge spoke to the MailOnline last week while taping for the show, where Klum hinted at her outlandish costume plans currently in the works. “It’s going to be extra. It’s going to be really extra. I have had sleepless nights over it, you know me,” she confessed. “I have to admit, I love it. And then my gut, I feel like it’s going to be good.” Last year, the German businesswoman shocked spectators by dressing in an all-too-realistic worm get-up, which took two years to make. Only the fashion mogul’s eyes peered through the thick and slimy coating of the cylinder costume. Speaking to the MailOnline, Klum admitted her team conveyed the same concerns over her desired look for this year as they did with her 2022 worm attire. “They were like, ‘A worm, really?’” Klum recalled in conversation with the outlet. “They kind of wanted me to think of a plan B and a plan C, but I’m not like that. For me, it is plan A.” “If you are thinking of all different other things, then it’s not going to be a success or it’s not going to be that major,” she continued. “Everyone around is always like: ‘Think of something different. This is crazy. And the worm is crazy.’” Though Klum’s been known to incorporate her husband and children in the storyline for her 31 October looks, she revealed her 2023 appearance will be a solo act. She admitted: “I never know if it will be good until the day, and I don’t want to let my Halloween fans down. There are so many creative people around the world and I don’t want to let them down.” The TV host has known her costume would only involve herself since 1 November last year, as that’s when she typically starts planning for the following year’s holiday. “When I wake up tomorrow, I start thinking of the next [costume],” Klum told People at her 2022 party. Klum’s bubbly textured invertebrate costume followed her intricate Zombie look and 2020 toilet paper mummy. The producer gravitates toward heavy makeup and facial reconfiguration for accuracy in every character. She’s rarely recognisable on the day, except for her eyes piercing through the thick mask made to look animated for every character. However, the style enthusiast took a break to seemingly celebrate herself in 2016, when she dressed as a Victoria’s Secret angel. Not only did Klum wear a renowned runway look from the intimates brand, but she convinced a squad of other women to mimic her look and reconstruct their facial features to look like her. In 2013, Klum decided to hit the fast-forward function on time and dressed like an old lady. The immaculate prosthetics, which included a wrinkled collarbone and varicose veins lining her neck, crafted a look so realistic that you’d think she was many years past her age - and not the then 40 years old that she was. Read More Heidi Klum denies she counts calories after facing backlash over reports she only eats 900 calories a day Heidi Klum’s model daughter Leni shows off grisly burn after admitting she ‘didn’t use enough sunscreen’ Heidi Klum opens up about her and husband Tom Kaulitz’s 16-year age gap 11 best kids’ Halloween outfits that will scare and delight 9 best horror stories to read this Halloween and beyond Kourtney Kardashian’s skeletons and other celebrity inspiration for Halloween

By Alistair Smout LONDON Britain is exploring designating its genomics sector as critical national infrastructure, Deputy Prime Minister

Sarah Burton is set to leave Alexander McQueen after serving as creative director for 13 years, the brand has announced. Burton, 49, was appointed to the role in 2010 following the death of Lee Alexander McQueen, having worked alongside the designer for 14 years. She was responsible for the creation of the wedding dress worn by the Princess of Wales, when she married Prince William in 2011. “I am so proud of everything I’ve done and of my incredible team at Alexander McQueen,” Burton said in a statement. “They are my family, and this has been my home for the past 26 years. I want to thank Francois-Henri Pinault for believing in me and offering me this amazing opportunity.” The label’s spring/summer 2024 collection, due to be unveiled at Paris Fashion Week later this month, will be her last. “Above all, I want to thank Lee Alexander McQueen,” Burton continued. “He taught me so much and I am eternally grateful to him. “I am looking forward to the future and my next chapter, and will always carry this treasured time with me.” François-Henri Pinault, chairman and CEO of parent company Kering, said: “I am immensely grateful to Sarah, and I want to personally thank her for her work over the past two decades, first alongside Lee Alexander McQueen, where her role was instrumental to his success, and then as the Creative Director since 2010. “Through her own experience, sensitivity and talent, Sarah continued to evolve the artistic expression of this iconic house. She kept and continued Lee’s heritage, attention to detail and unique vision, while adding her own personal, highly creative touch.” Gianfilippo Testa, CEO of Alexander McQueen, added: “We would like to express our immense gratitude to Sarah for writing such an important chapter in the history of the Alexander McQueen House. “Sarah’s contribution over the past 26 years will leave an indelible mark.” A new creative organisation will be announced in due course, the brand have said. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Sarah Burton to leave Alexander McQueen after 13 years as creative director What happens at a sexual health check-up? 9 arthritis myths we all need to stop believing

Artificial intelligence is using gallons upon gallons of water. Microsoft alone used more than 2,500 Olympic-sized swimming pools of water in its data centres last year. The latest numbers are leading to yet more questions about the sustainability and environmental dangers of the growth of artificial intelligence and related technology. Artificial intelligence requires vast computing resources, undertaking deeply complex calculations on behalf of people around the world. AI systems tend to be run in the cloud rather than on individual people’s computers, meaning that companies running them must operate vast server farms to deal with the queries of their users. Those server farms in turn need to pump in water to cool themselves down, because of the heat generated by those computers. That has long been a concern for environmentalists, but the sharp growth in artificial intelligence has led to even more use. Microsoft’s water consumption rose 34 per cent between 2021 and 2022, according to its latest environmental report, highlighted by the Associated Press. It was up to almost 1.7 billion gallons. Not all of that is from artificial intelligence. But Shaolei Ren, a researcher at the University of California, Riverside working to better understand the environmental impact of AI told the AP that the “majority of the growth” is because of the technology. Google also said that its water use had increased by 20 per cent over the same period. That varied across its different data centres, which are based in different parts of the US. For each 5 to 50 prompts, or questions, put to ChatGPT, it uses 500 millilitres of water, according to a paper that will be published by Professor Ren and his team later this year. Many technology companies have expressed concerns about their own water use, and how to minimise any negative effects of their data centres. The environmental concerns can be especially pressing because the use of water can be focused in particular areas around a data centre, meaning that the damage may not be spread. Google said last year for instance that “Wherever we use water, we are committed to doing so responsibly”. That includes analysing where water is being used and how much stress it might put on the surrounding area, for instance. Read More AI can help generate synthetic viruses and spark pandemics, warns ex-Google executive China’s ‘government-approved’ AI chatbot says Taiwan invasion likely Google launches AI to go to meetings for you

'Skyfall' actress Naomie Harris blocks out all the voices telling her what to wear on the red carpet.

PARIS Alexander McQueen creative director Sarah Burton will leave the Kering-owned fashion label after two decades, the latest

A software error coupled with a radar failure led to the loss of NASA's first Venus probe.

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