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Republican block means major branch of US military lacks a confirmed leader for first time in over a century
Republican block means major branch of US military lacks a confirmed leader for first time in over a century
A major branch of the US military does not have a Senate confirmed leader for the first time in more than a century, as a result of a Republican senator refusing to lift his block on military nominations.
2023-07-10 23:23
Scientists make surprising discovery that could help boost the global population
Scientists make surprising discovery that could help boost the global population
Infertility is a problem that afflicts more than a billion people across the world, which is why treatments such as IVF are so important. The procedure (in vitro fertilisation, to use it’s full name) involves the extraction of an egg from the woman's ovaries to be fertilised with sperm in a laboratory and returned to the woman’s womb. The goal is that the resulting embryo will then grow and develop into a foetus, blessing the parent or parents with a baby. However, success rates for IVF – as in, the percentage of treatments that result in a live birth – remain somewhat unencouraging: 32 per cent for women aged under 35; 25 per cent for women aged 35 to 37, with the numbers continuing to drop the older you get, according to the NHS. Nevertheless, a major new study has revealed a striking new finding which could help boost the hopes of countless aspiring mums and dads across the world. Sign up for our free Indy100 weekly newsletter After analysing 3,657 frozen embryos over a period of eight years, researchers in Western Australia found that IVF was much more likely to work when eggs had been harvested in the summer. The team clarified that it didn’t seem to matter when the embryos were transferred to the mother’s womb, just when the eggs were collected. Indeed, the likelihood of babies being born when the eggs had been retrieved in the summer was 30 per cent higher than when they had been retrieved in the autumn, according to the scientists. The team also found that the temperature on the day of egg collection didn’t seem to have an impact on success rates, but the number of sunny hours did. Of the embryos they tested, those harvested on days that had the most sunshine were 28 per cent more likely to result in a live birth compared to the darkest and most overcast days. “Our study suggests that the best conditions for live births appear to be associated with summer and increased sunshine hours on the day of egg retrieval,” the study’s lead, Dr Sebastian Leathersich, of Perth’s King Edward Memorial Hospital, said about the paper, which was published in the journal Human Reproduction. Still, he noted: “There are many factors that influence fertility treatment success, age being among the most important. “However, this study adds further weight to the importance of environmental factors and their influence on egg quality and embryonic development." He further explained: “We effectively separated the conditions at the time of egg collection from the conditions at the time of transfer, demonstrating that environmental factors when the eggs are developing are as, if not more, important than environmental factors during implantation and early pregnancy.” The expert obstetrician and gynaecologist added: “Optimising factors such as avoiding smoking, alcohol and other toxins and maintaining healthy activity levels and weight should be paramount. However, clinicians and patients could also consider external factors such as environmental conditions.” Despite Dr Leathersich and his colleagues concluding that the temperature on the day of egg collection had little bearing on the success of the process, they also found that the temperature on the day of embryo implantation did make a difference. The chances of a live birth rate decreased by 18 per cent when the embryos were transferred on the hottest days (when average temperatures measured between 14.5C and 27.8C) compared to the coolest days (0.1C to 9.8C), and there was a small increase in miscarriage rates, from 5.5 per cent to 7.6. The finding that miscarriage rates were highest when embryo transfer took place on the hottest days is consistent with other studies showing higher rates of miscarriage in the summer months. “This suggests that the negative effects of high temperature are more likely related to early pregnancy rather than egg development,” Dr Leathersich concluded. When it comes to the disparity in success rates between eggs retrieved in summer and autumn, he and his team pointed out that melatonin levels could be at play. Differences in lifestyles between the winter and summer months may also play a role, he and his colleagues acknowledged. "It is possible that there are differences in activity, diet, and lifestyle in different seasons which could underlie the observed differences in live birth rates, though such data were not collected in this study," they wrote. "It is also possible that other environmental factors, including pollutants, may impact clinical outcomes." Whilst the study’s findings are compelling, Dr Leathersich and his team admitted that it did have its limitations. The research was done in hindsight, using eggs that had been frozen, then thawed, so it could not draw watertight conclusions. “Ideally, these findings should be replicated in other sites with different conditions and different treatment protocols to confirm the findings,” Dr Leathersich said. “It would also be interesting to look at the impact of season and environmental factors on sperm parameters, as this could have contributed to our observations.” He added: “We are now planning to analyse this same group of patients using air quality data, as there may be seasonal changes in exposure to harmful pollutants which could negatively affect reproductive outcomes. “Finally, given the huge increase in so-called 'social egg freezing' for fertility preservation and the fact that this group generally have flexibility about when they choose to undergo treatment, it would be very interesting to see if these observations hold true with frozen eggs that are thawed and fertilised years later. “Any improved outcomes in this group could have big impacts for women making decisions about their future fertility, but the long-term follow-up required means it is likely to be some time before we can draw any conclusions for this population.” Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.
2023-07-10 23:22
Signed 'Great Gatsby' first edition to be offered in auction of Charlie Watts' book collection
Signed 'Great Gatsby' first edition to be offered in auction of Charlie Watts' book collection
A collection of first-edition books and jazz memorabilia belonging to the late Rolling Stones drummer Charlie Watts will go up for auction in September.
2023-07-10 20:52
Novo Weight Drugs Probed Over Reports of Suicidal Thoughts
Novo Weight Drugs Probed Over Reports of Suicidal Thoughts
Novo Nordisk A/S’s weight-loss medications are under investigation by the European Union’s drugs regulator after a small number
2023-07-10 20:18
Noel Gallagher's New York gig evacuated due to 'bomb threat'
Noel Gallagher's New York gig evacuated due to 'bomb threat'
Noel Gallagher's High Flying Birds was pulled and the venue evacuated amid "bomb threat" concerns.
2023-07-10 18:57
Black and Yellow rapper Wiz Khalifa sells part of his music catalogue
Black and Yellow rapper Wiz Khalifa sells part of his music catalogue
Wiz Khalifa has handed over the rights to his hits in the latest deal with HarbourView Equity Partners.
2023-07-10 18:53
All of the best looks from the Barbie world premiere
All of the best looks from the Barbie world premiere
Margot Robbie, Ryan Gosling, Issa Rae and all the stars of the Greta Gerwig-directed film graced the hot pink carpet of the Barbie world premiere in downtown LA. Australian actor Margot Robbie channelled the 1960s Solo in the Spotlight Barbie – and it’s the definition of the siren look. Robbie’s stylist Andrew Mukamal choose a black embellished rhinestone Schiaparelli strapless dress with a nylon net flounce at the bottom, and a red rose. She paired the glamourous number with a four-strand Lorraine Schwartz diamond choker, black arm-length gloves and black peep toe heels, while holding a pink chiffon pocket scarf. The Solo in the Spotlight Barbie has endured as a collectors’ favourite. Ryan Gosling brought the Ken-ergy with his Gucci plush two-piece suit and unbuttoned shirt in baby pink. He paired it with a Barbie pendent necklace, cream brogues, and was styled by Mark Avery. President Barbie Issa Rae and her stylist Wouri Vice had a custom moment with designer Marc Bouwer in a hot pink, key-hole gown, with a turtle neck and large bow. She wore it with her hair pulled back into a high pony tail, diamond drop-down earrings and a pink clutch bag. It was a full circle moment for rapper Nicki Minaj also known as the ‘original Barbie’ on the film’s soundtrack. Her outfit was inspired by the Diva Gone Platinum Barbie, and wore a grey ribbed crop top and wrap detail draped maxi skirt. Israeli model and actor Gal Gadot made a surprise appearance at the Barbie LA premiere, in an asymmetric JW Anderson brown pin-striped dress. Her hair was parted down the middle and pulled back into a sleek ponytail. Gadot paired the look with an white asymmetric bag and perspex heels. Doctor Strange star Xochitl Gomez wore a Dolce & Gabbana black and white gingham fishtail dress. She paired it with a black umbrella, black court heels and an elegant updo. Singer Dua Lipa – who stars as Mermaid Barbie and is on the film’s soundtrack with Billie Eilish and Nicki Minaj – wore an alluring silver sheer custom dress, with a square neckline detailing, and metallic silver pointed heels. The film’s writer, director, and executive producer Greta Gerwig arrived at the premiere in hot pink — from head to toe. She wore a pink blouse with a pussybow neckline that she tucked into a floor-length maxi skirt, and pink court heels. She paired the outfit with a pink oversized blazer she wore off the shoulder, and a pink mini Valentino bag.
2023-07-10 18:26
Margot Robbie 'can't imagine' any other Barbie director than Greta Gerwig
Margot Robbie 'can't imagine' any other Barbie director than Greta Gerwig
Margot Robbie thinks a lot of the 'Barbie' cast wouldn't have signed up for the film without director Greta Gerwig's involvement.
2023-07-10 18:26
The 1975 replace Lewis Capaldi at Reading and Leeds
The 1975 replace Lewis Capaldi at Reading and Leeds
The 1975 will perform their debut album in full at Reading and Leeds.
2023-07-10 17:16
Instagram Threads hits 100 million users, becoming easily the fastest growing app ever
Instagram Threads hits 100 million users, becoming easily the fastest growing app ever
Instagram’s Threads app has reached 100 million users, making it easily the fastest growing app ever. The site reached the number early on Monday morning, according to a tracker that looks at the numbers that are made public on each Threads account.
2023-07-10 15:59
Robert Pattinson was too 'busy' for Oppenheimer role
Robert Pattinson was too 'busy' for Oppenheimer role
Robert Pattinson helped inspired director Christopher Nolan to helm 'Oppenheimer'.
2023-07-10 15:22
Hunger haunts Ethiopia's Tigray region after years of war
Hunger haunts Ethiopia's Tigray region after years of war
By Dawit Endeshaw MEKELLE, Ethiopia Curled up on a hospital bed in Ethiopia's northern Tigray region, an emaciated
2023-07-10 15:22
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