Think of movies about the financial system and your mind is almost sure to go to Gordon Gekko and “Wall Street” or Leonardo DiCaprio’s gyrating Jordan Belfort in “The Wolf of Wall Street.”

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South Dakota regulators have denied a permit application for a proposed carbon dioxide pipeline project

Sepsis is an illness that affects nearly 50 million people worldwide each year, with around 11 million deaths attributed to the condition. In the United States, at least 1.7 million adults in the US develop sepsis annually, and nearly 270,000 die as a result, the Centres for Disease Control and Prevention (CDC) says. It affects 245,000 people in the UK each year, with around 48,000 deaths, according to the UK Sepsis Trust. World Sepsis Day commemorated on 13th September every year, strives to raise global awareness of the life-threatening condition. The day is seen as “an opportunity for people worldwide to unite in the fight against sepsis,” the Global Sepsis Alliance says. Here is everything you need to know about sepsis: What is sepsis? Sepsis Research says when the condition strikes, the immune system “overreacts” and begins to attack the infection and everything else around it “including the body’s own tissues and organs.” “Any type of infection — bacterial, viral or fungal — can lead to sepsis,” it adds. When sepsis occurs, it can cause inflammation and cause blood clotting around the body, if it does not get treated, it can result in death, organ failure and tissue damage, CDC says. Sepsis cannot be caught from another person, the NHS explains. What are the symptoms? The World Health Organisation (WHO) explains that the condition is a “medical emergency,” so if you think a person is exhibiting signs of sepsis or if you are showing signs – make sure you call 999 or go to the emergency room immediately. According to WHO, common signs and symptoms include: • Fever or low temperature and shivering • Confusion • Difficulty breathing • Clammy or sweaty skin • Extreme body pain or discomfort • High heart rate, weak pulse or low blood pressure • Low urine output Symptoms in children include: • Fast breathing • Convulsions • Pale skin • Lethargy • Difficulty waking up • Feeling cold to touch What are the causes? The Mayo Clinic says any type of infection can lead to sepsis and those that more commonly cause the condition include infections of: • Lungs, such as pneumonia • Kidney, bladder and other parts of the urinary system • Digestive system • Bloodstream • Catheter sites • Wounds or burns “Sepsis often presents as the clinical deterioration of common and preventable infections such as those of the respiratory, gastrointestinal and urinary tract, or of wounds and skin. Sepsis is frequently under-diagnosed at an early stage - when it still is potentially reversible,” the Global Sepsis Alliance says. Who is most at risk? The people most at risk of the condition, according to Mayo Clinic, are: • People with lower immune response, such as those being treated for cancer • People with human immunodeficiency virus (HIV). • People with chronic diseases such as diabetes kidney disease or chronic obstructive pulmonary disease (COPD). • people who are in intensive care or longer hospital stays. • People over the age of 65 • Infants How many cases are there globally? The WHO says a scientific publication estimated that in 2017 there were 48.9 million cases and 11 million sepsis-related deaths worldwide, which accounted for almost 20 per cent of all global deaths. That same year, almost half of all global sepsis cases occurred among children with an estimated 20 million cases and 2.9 million global deaths in children under 5 years of age. How can it be prevented? The Global Sepsis Alliance says the best to to avoid sepsis is by preventing infection. This can be done by undergoing vaccinations, ensuring that you only come into contact with clean water, washing your hands properly and if you are giving birth - making sure it is in a clean and sterilised environment. Can sepsis be treated? Sepsis can be treated with appropriate treatment such as antibiotics – this should be given as soon as possible. The CDC says sometimes “surgery is required to remove tissue damaged by the infection”. “Antibiotics are critical tools for treating life-threatening infections, like those that can lead to sepsis,” the CDC adds. Read More 5 things everyone needs to know about eczema 13 potential cancer symptoms you should get checked out How can I improve my teenager’s low mood? Duran Duran’s Andy Taylor says he’s ‘asymptomatic’ after end-of-life diagnosis Nine hours of parallel surgery: how Britain’s first womb transplant was carried out Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’

The fashion designer who created the wedding dress of Kate Middleton, Princess of Wales, is stepping down as creative director at Alexander McQueen after two decades at the brand, luxury group Kering said

ORLANDO, Fla.--(BUSINESS WIRE)--Sep 11, 2023--

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Heidi Klum is prepping for the debut of her own creation – her 2023 Halloween costume. From a flesh-eating alien to Fiona and a sparkly firework, the 50-year-old supermodel not only stunts on high-fashion runways but on the red carpet for the spookiest night of the year. It’s safe to say Klum’s love for dressing up isn’t just haute couture. She’s a costume enthusiast as well, and the mother of three is already preparing to assume her character for this year’s Halloween celebration. The America’s Got Talent judge spoke to the MailOnline last week while taping for the show, where Klum hinted at her outlandish costume plans currently in the works. “It’s going to be extra. It’s going to be really extra. I have had sleepless nights over it, you know me,” she confessed. “I have to admit, I love it. And then my gut, I feel like it’s going to be good.” Last year, the German businesswoman shocked spectators by dressing in an all-too-realistic worm get-up, which took two years to make. Only the fashion mogul’s eyes peered through the thick and slimy coating of the cylinder costume. Speaking to the MailOnline, Klum admitted her team conveyed the same concerns over her desired look for this year as they did with her 2022 worm attire. “They were like, ‘A worm, really?’” Klum recalled in conversation with the outlet. “They kind of wanted me to think of a plan B and a plan C, but I’m not like that. For me, it is plan A.” “If you are thinking of all different other things, then it’s not going to be a success or it’s not going to be that major,” she continued. “Everyone around is always like: ‘Think of something different. This is crazy. And the worm is crazy.’” Though Klum’s been known to incorporate her husband and children in the storyline for her 31 October looks, she revealed her 2023 appearance will be a solo act. She admitted: “I never know if it will be good until the day, and I don’t want to let my Halloween fans down. There are so many creative people around the world and I don’t want to let them down.” The TV host has known her costume would only involve herself since 1 November last year, as that’s when she typically starts planning for the following year’s holiday. “When I wake up tomorrow, I start thinking of the next [costume],” Klum told People at her 2022 party. Klum’s bubbly textured invertebrate costume followed her intricate Zombie look and 2020 toilet paper mummy. The producer gravitates toward heavy makeup and facial reconfiguration for accuracy in every character. She’s rarely recognisable on the day, except for her eyes piercing through the thick mask made to look animated for every character. However, the style enthusiast took a break to seemingly celebrate herself in 2016, when she dressed as a Victoria’s Secret angel. Not only did Klum wear a renowned runway look from the intimates brand, but she convinced a squad of other women to mimic her look and reconstruct their facial features to look like her. In 2013, Klum decided to hit the fast-forward function on time and dressed like an old lady. The immaculate prosthetics, which included a wrinkled collarbone and varicose veins lining her neck, crafted a look so realistic that you’d think she was many years past her age - and not the then 40 years old that she was. Read More Heidi Klum denies she counts calories after facing backlash over reports she only eats 900 calories a day Heidi Klum’s model daughter Leni shows off grisly burn after admitting she ‘didn’t use enough sunscreen’ Heidi Klum opens up about her and husband Tom Kaulitz’s 16-year age gap 11 best kids’ Halloween outfits that will scare and delight 9 best horror stories to read this Halloween and beyond Kourtney Kardashian’s skeletons and other celebrity inspiration for Halloween